There have been several questions recently about how to set a quality requirement, specifically a precision requirement, for the high sensitivity C-reactive protein test (hs-CRP). There certainly is a lot of interest and demand for hs-CRP these days because of published studies that show a correlation of elevated baseline values with a higher risk of future cardiovascular events. Cardiologists are clamoring for the test because of the discussions in the scientific literature and professional meetings.

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