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Analysis of common cortisol assays

Clinical Chemistry had a comprehensive review of the performance of routine serum cortisol assays, including performance on different patient cohorts of males, nonpregnant females, pregnant females, and those under different drug regimens. Is the analytical performance the same for all of these patients? And if not, how big are the differences and how do we finally judge the method performance? Does a Sigma-metric analysis clarify the picture at all?

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